MAD - VVI

£294 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Search hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
In the last 7 days, travellers have searched 41,299,237 times on KAYAK, and here's why:

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Cheap Flight Deals from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent return flight deals from Madrid to Santa Cruz de la Sierra

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Madrid to Santa Cruz de la Sierra.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
10:55 - 02:00MAD-VVI
20h 05m1 stop
03:05 - 22:35VVI-MAD
14h 30m1 stop
£575Avianca
Find Deal
Mon, 10 Feb - Sun, 23 Feb
10:55 - 02:00MAD-VVI
20h 05m1 stop
03:05 - 22:35VVI-MAD
14h 30m1 stop
£576Avianca
Find Deal
Mon, 3 Feb - Wed, 12 Feb
22:35 - 02:00MAD-VVI
32h 25m2 stops
03:05 - 22:00VVI-MAD
37h 55m2 stops
Thu, 30 Jan - Thu, 6 Feb
00:45 - 04:45MAD-VVI
33h 00m1 stop
05:25 - 16:15VVI-MAD
29h 50m1 stop
£693LATAM Airlines
Find Deal
Sun, 2 Feb - Thu, 13 Feb
00:45 - 04:45MAD-VVI
33h 00m1 stop
05:25 - 11:25VVI-MAD
25h 00m2 stops
£703LATAM Airlines
Find Deal
Sun, 2 Feb - Thu, 13 Feb
06:00 - 02:00MAD-VVI
26h 00m2 stops
13:10 - 18:50VVI-MAD
23h 40m2 stops
Thu, 22 May - Mon, 9 Jun
23:35 - 05:55MAD-VVI
11h 20mdirect
13:30 - 05:10VVI-MAD
10h 40mdirect
£958Air Europa
Find Deal
Mon, 3 Feb - Thu, 13 Feb
23:35 - 05:55MAD-VVI
11h 20mdirect
13:30 - 05:10VVI-MAD
10h 40mdirect
£959Air Europa
Find Deal
Mon, 3 Feb - Thu, 13 Feb
11:15 - 22:20MAD-VVI
41h 05m2 stops
01:15 - 08:05VVI-MAD
24h 50m2 stops
£962United Airlines
Find Deal
Fri, 11 Apr - Sun, 27 Apr
11:15 - 22:04MAD-VVI
39h 49m2 stops
00:52 - 09:15VVI-MAD
27h 23m2 stops
£1,336United Airlines
Find Deal
Sun, 2 Feb - Mon, 17 Feb

Flights from Madrid to Santa Cruz de la Sierra - Travel Insights & Trends

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.
Your flight ticket price will generally be cheaper if you fly to Santa Cruz de la Sierra on a Wednesday and more expensive on a Sunday. On your return trip to Madrid, you should consider flying back on a Wednesday, and avoid Mondays for better deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Madrid to Santa Cruz de la Sierra is May, where tickets cost £640 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is £1,118 and £1,083 respectively.

Can I save money by flying with a stopover from Madrid to Santa Cruz de la Sierra?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.
Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 2 stops stopover the cheapest option at £764 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know - Cheap tickets from Madrid to Santa Cruz de la Sierra

Low season

April

High season

December

Cheapest flight

£294
Best time to beat the crowds (16% less expensive on average)
Most popular time to fly (37% more expensive on average)
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was £365 for a one-way ticket and £714 for a return.

  • Which airports will I be using when flying from Madrid to Santa Cruz de la Sierra?

    Madrid and Santa Cruz de la Sierra are both served by 1 main airport. You will leave Madrid from Madrid Barajas and will be arriving at Santa Cruz de la Sierra Viru Viru Intl.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, Lufthansa, and Vueling offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    oneworld, and SkyTeam are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a direct flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, LATAM Airlines or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are LATAM Airlines and Iberia. With an average price for the route of £839 and an overall rating of 7.5, LATAM Airlines is the most popular choice. Iberia is also a great choice for the route, with an average price of £653 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

KAYAK’s top tips for finding a cheap flight from Madrid to Santa Cruz de la Sierra

  • Looking for a cheap flight from Santa Cruz de la Sierra to Madrid? 25% of our users found flights on this route for £609 or less round-trip.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa

Air Europa

Wednesday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Friday

BoA, Iberia

BoA, Iberia

Sunday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Tuesday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Thursday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Saturday

BoA, Iberia

BoA, Iberia

See more direct flights
See more direct flights

Top 5 airlines serving from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1844 reviews
7.0Entertainment
8.0Crew
7.6Boarding
7.3Comfort
6.7Food
Airline reviews

Only complaint is that the entertainment system wasn’t working on our seats and some others.

6.0 GoodJohn, Dec 2024ATL - LIM
Read more LATAM Airlines reviews

Only complaint is that the entertainment system wasn’t working on our seats and some others.

The flight itinerary was changed 3 times, I explain the problem on the previous leg.

Flight never happened because of previous flight delay. Sent back to the stays on a flight 10 hrs later without making to my final destination and still waiting full rugindo for it. So yeah not a good experience

Four handbag storages were damaged and sealed, limiting the space to store our things in the plane.

It was fine. no food or entertainment , but was only a 40 minute flight.

The boading process was fine. Had to wait for bus from tarmac to terminal. Had to go through 2 or 3 security checkpoints in Lima to make next connecting flight.

It was a short flight, sits uncomfortable No food was provided. Staff was lovely and kind .

The sits were very hard and after an overnight flight my back was hurting. The food was very bad and poor quality, I was very hungry but I could not eat the food, I tried but the it was so bad , I don’t think my dog would have eaten it either. No kidding?!!! The Crew was lovely, the bathrooms were spacious and the entertainment was good. When I arrived in Madrid I was given the incorrect instructions by the woman who was at the desk for connecting flights information for LATAM airlines. Due to this I missed my flight and my luggage was lost. Consequently I had 3 passport checks and security checks in and out of Spain!!! The terminal T4 and terminal T4S are a different thing And they are very far apart. My flight was scheduled to exit at T4S and they send me to T4, I went to T4 they send me back to T4S and I had yo take a train and check in and out this time I was exhausted and wanted to cry. Eventually a crew member of LATAM felt compassion for me and saw my predicament, she said I had no time to go back to terminal T4 again so she rescheduled the flight. My baggage was lost and I had to go to try to find it at midnight. It was a real nightmare. Just thinking about it makes me angry. This Airport in Madrid is not easy to navigate, so please give people some real assistance and assurance. I SHOULD have not missed my flight There was plenty of time. It was miss information of people who don’t care, don’t read and don’t listen and unfortunately that is their job. Not happy at all

No food optional ( they offer just pasta, no second option, the soda without carbonation, I asked for snacks and they said give a minute, I never got it) I believe they (crew) don't care about it (people)

The seats are getting smaller and smaller. Very uncomfortable trip. More than in other airlines

All flights with Air Europa you arrive late to the connections of other flights, I missed my train, I had to pay for my train again, the crew are antisocial, you are paying for a service, it is not free, thanks to the travelers they are there, it is the last time I fly with them,

Terrible experience - we won’t be flying with Air Europa again

The crew was not kind , just doing their job but very cold people

The insanely long lines at customs were chaotic and stressful. They also created a lot of stress among passengers. Including fights and threats. The hot food I purchased was cold, barely edible. The check in staff and crew were nice and the pilot good but the overall experience was very disappointing. Passengers were still insulting each other upon arrival.

No frills airlines. Tickets were reasonably priced for a short-term booking. But comfort is a big issue.

It was just okay. They overcharged me for a checked bag because I didn’t know it wasn’t included in the airfare.

Very small dinner, NO breakfast. You have to buy an earphone.

Food was terrible. No breakfast. Will not use this airline.

I'm not going to travel with that airline again.

I travel on a monthly basis and I’m not a stranger to budget airlines. I never complain about anything, it just about adjusting you expectations to what you paid for and you will get, but these flights (2) with Air Europa Miami - Madrid - Athens were a terrible experience. Both flights had a significant delays and multiple gate changes. At the checking they used a hand scale to weight your carry in, it cannot be more than 10 kg , even it fit on size.Luckily mine was ok . The food was inedible. The staff service was ok, but you can totally tell they do not care about much and show little customer service culture. I think this was my last trip on Air Europa. Actually the price was almost the same than other major airlines, I just took this one because I needed to depart late at night.

At Barcelona, you have to get your passports checked before going to the E gates so give yourself time for that. The restaurants around the D and E gates are really limited compared to prior to passport control. On boarding, the gate staff tried to charge me EUR100 for my carryon, saying it was too big. I put it in their ‘measurement box’ and it fit with the top slightly protruding where the handle was. The gate staff then said my bag was ok to carry and put an ‘approved’ tag on my bag. I was bussed to the plane I boarded a ‘Level’ carrier which I had not heard of before. If you booked through a code share like American, you will be served food and alcohol on the plane. They do not provide complimentary ear phones or blankets. The internet was free but only for texting. WhatsApp worked but Spotify did not. Entertainment choice was adequate, movies were old and selection was limited. On arrival at LAX, my checked in bag was damaged as the wheel was broken. I am taking this up with Iberia. Their website and customer service was moderate in terms of user friendliness. You have to have all your documents and prepared to be patient and persistent. Let’s see how this goes. All n all, for the price I paid, I would recommend Level.

Excellent with no delays and according to the time schedule.

Its a bus taking you on and off the plane so if you have big luggage … more muscles needed

Flight LIN MAD. Checkin was fine (but I must admit that being a Platinum member I skip the lines). Security was fine (they have the new machines where you need not take laptops or liquids out). Longe was OK (BA). Boarding was a mess, the boarding gate personnel were rude and some should simply not be in a customer facing position. Flight in itself was fine, usual Iberia European coach. We were on time and actually time to deliver luggage was better than normal for Barajas

Bad business class. Staff totally not helping. Lights and chargers not working

Great food, excellent service. Did not manage to make wifi work but in a flight of less than an hour it was not a big deal

Very well, except that my luggage didn’t arrive in the corresponding flight, but they brought to me the next day.

Was very unhappy with the entire process, from check in to boarding to the comfort of the flight. Did not enjoy the flight on Level.

The boarding was a nightmare. Iberia would not let me check in in advance. They then refused to issue a boarding pass in Paris and said I would get the boarding pass in Madrid. In Madrid, there was no transit desk, no help. I had to run around and find someone to issue the pass. I only had an hour and risked missing the connection. Only at the gate did Iberia tell me they were overbooked and had downgraded me. I was stressed, exhausted, almost missed the connection because of Iberia’s conduct. Unacceptable.

When having a connection at Madrid, it’s extremely confusing. You must travel from your arrival gate, all the way down stairs to a security check point, go up stairs, then downstairs to another security check. Then make your way to your gate. All the while traveling through a “mall” inside the airport which makes it difficult. 10/10 don’t recommend connecting flights through Madrid.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

I enjoyed it! In that case, I should have been offered this choice. On my first trip to Miami, I was asked to pay $320 for my luggage just for getting it totally broken. I cannot accept this situation at all!!!!

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

My whole return flight itinerary, 3 flights, got canceled without any warning to me because I missed one of the earlier flights 3 weeks ago

Boarding, crew and food. Seats are too small Love Avianca

Charging for WATER on a SIX hour flight in repugnant. Enough said!

Poor In food , poor in entertainment , passengers don’t get for free not even water

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

BOA airplanes are so old and dirty, the bathroom was so nasty, it smelled so bad and had tape all over the cabinets. My chair wouldn't recline, we had no entertainment, the flight was super cold. The only positive thing about this flight is that I feel it's so old that they even serve food, like in the past! I travel a lot and nowadays the companies only serve some snacks or sometimes offer something to eat if you pay. Not the case with this flight. Never again flying with BOA. They are definetly the worst.

This airline is always THE WORST. They seem to have flights moving to other times (late) 90% of the time. The airplanes are old, and the landing (i really don't know why) is 90% of the time shaky. I actually never buy tickets from BOA, I prefer other airlines by far.

Book cheap flights from Madrid to Santa Cruz de la Sierra

Cheapest flights to Santa Cruz de la Sierra from Madrid found in 2025

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Madrid to Santa Cruz de la Sierra found on KAYAK in the last 72 hours.
2/2Sun
directIberia
11h 30mMAD-VVI
£294
2/2Sun
directIberia
11h 30mMAD-VVI
£295
9/2Sun
1 stopLATAM Airlines
33h 00mMAD-VVI
£302
9/2Sun
directBoA
11h 30mMAD-VVI
£308
7/2Fri
directIberia
11h 30mMAD-VVI
£310
6/2Thu
1 stopLATAM Airlines
33h 00mMAD-VVI
£323
10/2Mon
1 stopLATAM Airlines
20h 35mMAD-VVI
£336
10/2Mon
directAir Europa
11h 20mMAD-VVI
£347
2/2Sun
1 stopAvianca
20h 05mMAD-VVI
£405
2/2Sun
1 stopAvianca
20h 05mMAD-VVI
£405

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Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

Information on your arrival and departure airports

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